Dr Anna Hoerder-Suabedissen

I completed a BSc in Natural Sciences at Lancaster University, before moving to Oxford to undertake an MSc in Neuroscience. There, I also obtained my DPhil in Developmental Neuroscience, and have worked as a post-doctoral researcher in different labs in the Department of Physiology, Anatomy and Genetics since. I have been a lecturer in Neuroscience at Keble College and Trinity College.

Teaching

At St John's, I mainly teach for the final honours school theme 'Wiring up the brain', as well as contributing to the synoptic and critical appraisal paper teaching for FHS students.

My research interest is in early brain development. In my current work, I determine ways to identify the claustrum in developing mouse brains. The adult claustrum is widely interconnected with most part of the cortex, and single neurons often project to many different cortical regions. Finding ways to delineate the claustrum during development has helped us to determine when claustrum neurons first form connections to other parts of the cortex. This occurs relatively late during mouse brain development, and the timing may be relevant to the emergence of particular features of sleep.

Selected publications

Hoerder-Suabedissen A., Ocana-Santero G., Draper T. H., Scott S. A., Kimani J., Shelton A. M., Butt S. J. B., Molnár Z, Packer A. M. (2022). Temporal origin of mouse claustrum and development of its cortical projections

Krone L. B. , Yamagata T., Blanco-Duque C., Guillaumin M. C. C., Kahn M. C., van der Vinne V., McKillop L. E., Tam S. K. E., Peirson S. N., Akerman C. J., Hoerder-Suabedissen A., Molnár Z., Vyazovskiy V. V. (2021) A role for the cortex in sleep-wake regulation. Nat Neuroscience 24(9):1210–15

Hayashi S., Hoerder-Suabedissen A., Kiyokage E., Maclachlan C., Toida K., Knott G., Molnár Z. (2021). Maturation of complex synaptic connections of L5 cortical axons in the posterior thalamic nucleus requires SNAP25. development of layer 5 corticothalamic projections in posterior thalamic nucleus depends on regulated vesicular release Cer Cortex 31(5): 2625–38

Hoerder-Suabedissen A., Korrell K., Hayashi S., Ramirez D. O., Grant E., Jeans A., Christian H. C., Kavalali E., Wilson M. C., Molnár Z. (2019) Cell-specific loss of SNAP25 from cortical projection neurons allows normal development but causes subsequent neurodegeneration. Cereb Cortex, 29(5): 2148–59

Hoerder-Suabedissen A., Hayashi S., Upton L., Nolan Z., Casas D., Grant E., Korrell K. V., Clasca F., Kanold P., Molnár Z. (2018) Cortical Layer 6b neurons selectively innervate higher order nuclei in the thalamus. Cereb Cortex 28(5):1882–97.