Dr Auguste Vadisiute

I joined St John’s as a Junior Research Fellow in October 2022. I completed my DPhil in the laboratory of Zoltan Molnar in the Department of Physiology, Anatomy and Genetics at the University of Oxford and at Christ Church (Oxford). For my DPhil research, I examined the role of microglia in activity-dependent neuronal network maturation and maintenance. I also hold BSc in Medical Genetics and MSc in Neurobiology.

Teaching

I am happy to be contacted by prospective Part 2, FHS and/or undergraduate project students.

My research interests lie in the role of the immune system during brain development. Specifically, the role of microglial cells interaction with developing neuronal network in sex-specific manner and their involvement in neurodevelopmental disorders such as autism and schizophrenia.

Selected publications

'The role of snare proteins in cortical development', Developmental Neurobiology, 2022

'Differential effect on myelination through abolition of activity‐dependent synaptic vesicle release or reduction of overall electrical activity of selected cortical projections in the mouse', Journal of Anatomy, 2019

'Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction', Nature Communication, 2018

'Sexual dimorphism in microglia and synapses during mouse postnatal development', Developmental Neurobiology, 2017

Awards and distinctions

2021, Goodger and Schorstein Scholarship, University of Oxford